{"license":"https://creativecommons.org/licenses/by/4.0/","about":"The input of the Perfume Autopsy for a teaching accord: its teaching variants (each labelled \"teaching variant, modeled\") and their components, read from the records named in each field. The model reuses the Causal Debugger’s model; everything it computes is modeled. Not a commercial perfume formula and not any real perfume’s formula.","accord":"rose-teaching-accord","name":"A rose, from four molecules","version":3,"updated":"2026-09-30","disclaimer":"A teaching accord for learning: not a commercial perfume formula, not a finished perfume, not safety-assessed; do not make it for skin.","href":"/perfumery/accord/rose-teaching-accord.html","halfLife":{"top":1.5,"heart":6,"base":12,"ev":{"e":"modeled","n":"the site constants of the evaporation simulator on /science for limonene (its Top note), Hedione (Heart) and Ambroxan (Base); “chosen for the simulator and are not measurements”"}},"components":[{"key":"phenylethyl-alcohol","id":"phenylethyl-alcohol","type":"molecule","name":"2-phenylethyl alcohol","href":"/perfumery/molecule/phenylethyl-alcohol.html","onRecord":true,"role":"heart","roleEv":{"e":"documented","s":[{"t":"Kleoff et al. (2022). Synthesis of odorants in flow and their applications in perfumery","h":"https://doi.org/10.3762/bjoc.18.76"}],"q":"Floral notes, such as rose, jasmine, orange blossom, or lavender, are typically middle notes defining the “heart” of many perfumes","c":"A","n":"the review names rose among the floral heart notes"},"vol":null,"volEv":{"n":"no volatility class on record for phenylethyl-alcohol"},"desc":["floral","honey"],"descEv":{"e":"documented","s":[{"t":"Kreissl et al. (2022). Leibniz-LSB@TUM Odorant Database, Version 1.2","h":"https://www.leibniz-lsb.de/en/databases/leibniz-lsbtum-odorant-database/"}],"q":"2-phenylethanol | CAS 60-12-8 | Odor quality: floral, honey-like","c":"A","v":"floral, honey-like"},"mols":[{"id":"phenylethyl-alcohol","name":"phenylethyl alcohol"}],"molsNote":null,"thr":{"v":140,"unit":"µg/kg","medium":"water","method":"orthonasal odour detection threshold in water, determined by the method of Czerny et al. 2008, Eur Food Res Technol 228:265–273, as the database states","ev":{"e":"measured","s":[{"t":"Kreissl et al. (2022). Leibniz-LSB@TUM Odorant Database, Version 1.2","h":"https://www.leibniz-lsb.de/en/databases/leibniz-lsbtum-odorant-database/"}],"c":"A","n":"the retronasal threshold in the same study is 390 µg/kg (OT-1)"}},"thrNote":null,"regs":[],"regEv":{"n":"no Regulation record yet"},"prov":[{"t":"occurs in rose absolute","href":"/perfumery/material/rose-absolute.html","ev":{"e":"measured","s":[{"t":"Çevikbaş et al. (2024). Exploring rose absolute and phenylethyl alcohol as novel quorum sensing inhibitors in Pseudomonas aeruginosa and Chromobacterium violaceum","h":"https://doi.org/10.1038/s41598-024-66888-z"}],"q":"rose absolute and its primary component, phenylethyl alcohol","c":"A","n":"GC-2 agrees: \"the main constituent of rose absolute\" (one sample)"}},{"t":"occurs in rose otto","href":"/perfumery/material/rose-otto.html","ev":{"e":"documented","s":[{"t":"Xiao et al. (2017). Verification of key odorants in rose oil by gas chromatography-olfactometry/aroma extract dilution analysis, odour activity value and aroma recombination","h":"https://doi.org/10.1080/14786419.2017.1303693"}],"q":"phenyl ethyl alcohol","c":"A"}},{"t":"no price: nothing on this site is for sale","ev":{"e":"house rule","n":"nothing on the site is for sale; no price is filed for molecules"}}]},{"key":"citronellol","id":"citronellol","type":"molecule","name":"citronellol","href":"/perfumery/molecule/citronellol.html","onRecord":true,"role":"heart","roleEv":{"e":"documented","s":[{"t":"Kleoff et al. (2022). Synthesis of odorants in flow and their applications in perfumery","h":"https://doi.org/10.3762/bjoc.18.76"}],"q":"Floral notes, such as rose, jasmine, orange blossom, or lavender, are typically middle notes defining the “heart” of many perfumes","c":"A","n":"the review names rose among the floral heart notes"},"vol":null,"volEv":{"n":"no volatility class on record for citronellol"},"desc":["soapy","rose"],"descEv":{"e":"documented","s":[{"t":"Kreissl et al. (2022). Leibniz-LSB@TUM Odorant Database, Version 1.2","h":"https://www.leibniz-lsb.de/en/databases/leibniz-lsbtum-odorant-database/"}],"q":"β-citronellol | CAS 106-22-9, 1117-61-9, 7540-51-4 | Odor quality: soapy, rose-like","c":"A","v":"soapy, rose-like"},"mols":[{"id":"citronellol","name":"citronellol"}],"molsNote":null,"thr":null,"thrNote":"no single value: the record is the unspecified compound (CAS 106-22-9) and the filed measurements are per enantiomer, (R) 10 µg/kg and (S) 4.9 µg/kg in water (OT-1, Schaller and Schieberle 2020)","regs":["eu-2009-1223","eu-2023-1545"],"regEv":{"e":"documented","s":[{"t":"Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products…","h":"https://eur-lex.europa.eu/eli/reg/2009/1223/oj"},{"t":"Commission Regulation (EU) 2023/1545 of 26 July 2023 (labelling of fragrance allergens)","h":"https://eur-lex.europa.eu/eli/reg/2023/1545/oj"}],"q":"86 Citronellol/(±) -3,7-dimethyloct-6-en-1-ol Citronellol 106-22-9/26489-01-0","c":"A","n":"a house review: the Regulation records that apply to it (educational summaries as of 2026-09-30; not legal advice)"},"prov":[{"t":"occurs in rose otto","href":"/perfumery/material/rose-otto.html","ev":{"e":"measured","s":[{"t":"Kumar et al. (2023). Phenotyping floral traits and essential oil profiling revealed considerable variations in clonal selections of damask rose (Rosa damascena Mill.)","h":"https://doi.org/10.1038/s41598-023-34972-5"}],"q":"citronellol (20.35-44.75%) and geraniol (15.63-27.76%) were highest","c":"A","n":"the range is one study’s and is not shown as a share"}},{"t":"occurs in rose absolute","href":"/perfumery/material/rose-absolute.html","ev":{"e":"measured","s":[{"t":"Çevikbaş et al. (2024). Exploring rose absolute and phenylethyl alcohol as novel quorum sensing inhibitors in Pseudomonas aeruginosa and Chromobacterium violaceum","h":"https://doi.org/10.1038/s41598-024-66888-z"}],"c":"A"}},{"t":"no price: nothing on this site is for sale","ev":{"e":"house rule","n":"nothing on the site is for sale; no price is filed for molecules"}}]},{"key":"geraniol","id":"geraniol","type":"molecule","name":"geraniol","href":"/perfumery/molecule/geraniol.html","onRecord":true,"role":"heart","roleEv":{"e":"documented","s":[{"t":"Kleoff et al. (2022). Synthesis of odorants in flow and their applications in perfumery","h":"https://doi.org/10.3762/bjoc.18.76"}],"q":"Floral notes, such as rose, jasmine, orange blossom, or lavender, are typically middle notes defining the “heart” of many perfumes","c":"A","n":"the review names rose among the floral heart notes"},"vol":null,"volEv":{"n":"no volatility class on record for geraniol"},"desc":["rose","citrus"],"descEv":{"e":"documented","s":[{"t":"Kreissl et al. (2022). Leibniz-LSB@TUM Odorant Database, Version 1.2","h":"https://www.leibniz-lsb.de/en/databases/leibniz-lsbtum-odorant-database/"}],"q":"geraniol | CAS 106-24-1 | Odor quality: rose-like, citrus-like","c":"A","v":"rose-like, citrus-like"},"mols":[{"id":"geraniol","name":"geraniol"}],"molsNote":null,"thr":{"v":1.1,"unit":"µg/kg","medium":"water","method":"orthonasal odour detection threshold in water, determined by the method of Czerny et al. 2008, Eur Food Res Technol 228:265–273, as the database states","ev":{"e":"measured","s":[{"t":"Kreissl et al. (2022). Leibniz-LSB@TUM Odorant Database, Version 1.2","h":"https://www.leibniz-lsb.de/en/databases/leibniz-lsbtum-odorant-database/"}],"c":"A","n":"the retronasal threshold in the same study is 2.5 µg/kg (OT-1)"}},"thrNote":null,"regs":["eu-2009-1223"],"regEv":{"e":"documented","s":[{"t":"Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products…","h":"https://eur-lex.europa.eu/eli/reg/2009/1223/oj"}],"q":"78 2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)- Geraniol 106-24-1","c":"A","n":"a house review: the Regulation records that apply to it (educational summaries as of 2026-09-30; not legal advice)"},"prov":[{"t":"occurs in rose otto","href":"/perfumery/material/rose-otto.html","ev":{"e":"measured","s":[{"t":"Kumar et al. (2023). Phenotyping floral traits and essential oil profiling revealed considerable variations in clonal selections of damask rose (Rosa damascena Mill.)","h":"https://doi.org/10.1038/s41598-023-34972-5"}],"q":"citronellol (20.35-44.75%) and geraniol (15.63-27.76%) were highest","c":"A","n":"the range is one study’s and is not shown as a share"}},{"t":"occurs in rose absolute","href":"/perfumery/material/rose-absolute.html","ev":{"e":"measured","s":[{"t":"Çevikbaş et al. (2024). Exploring rose absolute and phenylethyl alcohol as novel quorum sensing inhibitors in Pseudomonas aeruginosa and Chromobacterium violaceum","h":"https://doi.org/10.1038/s41598-024-66888-z"}],"c":"A"}},{"t":"no price: nothing on this site is for sale","ev":{"e":"house rule","n":"nothing on the site is for sale; no price is filed for molecules"}}]},{"key":"beta-damascenone","id":"beta-damascenone","type":"molecule","name":"β-damascenone","href":"/perfumery/molecule/beta-damascenone.html","onRecord":true,"role":"trace","roleEv":{"e":"perfumery convention","c":"B","n":"a trace: its odour threshold on record is very low (the molecule record), so a trace is enough by convention"},"vol":null,"volEv":{"n":"no volatility class on record for beta-damascenone"},"desc":["rose","fruity","jammy"],"descEv":{"e":"house interpretation","c":"C","n":"the house’s own odour words on the page’s MOLS entry; no descriptor source is filed","v":"rose, fruity, jammy"},"mols":[{"id":"beta-damascenone","name":"β-damascenone"}],"molsNote":null,"thr":{"v":0.006,"unit":"µg/kg","medium":"water","method":"orthonasal odour detection threshold in water, determined by the method of Czerny et al. 2008, Eur Food Res Technol 228:265–273, as the database states","ev":{"e":"measured","s":[{"t":"Kreissl et al. (2022). Leibniz-LSB@TUM Odorant Database, Version 1.2","h":"https://www.leibniz-lsb.de/en/databases/leibniz-lsbtum-odorant-database/"}],"c":"A","n":"about six parts per trillion by mass. The Leibniz-LSB@TUM database lists the (E)-isomer (CAS 23726-93-4; this record’s PubChem CID is the (E)-isomer). The figures the site once gave (in water and in air) came from a proprietary compilation (OT-4, a source the house does not use), withdrawn as a source on 2026-09-30, and are not repeated; the database’s air values for β-damascenone are 0.002–0.004 ng/L, Blank et al. 1992 (OT-1).."}},"thrNote":null,"regs":["ifra-rose-ketones"],"regEv":{"e":"documented","s":[{"t":"International Fragrance Association (IFRA)","h":"https://d3t14p1xronwr0.cloudfront.net/docs/standards/IFRA_STD_077.pdf"}],"q":"CAS-No.: 23696-85-7","c":"A","n":"a house review: the Regulation records that apply to it (educational summaries as of 2026-09-30; not legal advice)"},"prov":[{"t":"occurs in rose otto","href":"/perfumery/material/rose-otto.html","ev":{"e":"documented","s":[{"t":"Huang et al. (2009). Substrate promiscuity of RdCCD1, a carotenoid cleavage oxygenase from Rosa damascena","h":"https://doi.org/10.1016/j.phytochem.2009.01.020"}],"q":"Several of the key flavor compounds in rose essential oil are C(13)-norisoprenoids, such as beta-damascenone","c":"A"}},{"t":"occurs in rose absolute","href":"/perfumery/material/rose-absolute.html","ev":{"e":"inferred","s":[{"t":"Huang et al. (2009). Substrate promiscuity of RdCCD1, a carotenoid cleavage oxygenase from Rosa damascena","h":"https://doi.org/10.1016/j.phytochem.2009.01.020"}],"c":"C","n":"S5 speaks of the essential oil; the absolute is inferred"}},{"t":"no price: nothing on this site is for sale","ev":{"e":"house rule","n":"nothing on the site is for sale; no price is filed for molecules"}}]}],"regs":{"eu-2009-1223":{"name":"Regulation (EC) No 1223/2009 on cosmetic products","body":"EU","kind":"a labelling condition (Annex III): named in the list of ingredients above a stated concentration; and prohibitions (Annex II)","href":"/perfumery/regulation/eu-2009-1223.html","ev":{"e":"documented","s":[{"t":"Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products…","h":"https://eur-lex.europa.eu/eli/reg/2009/1223/oj"}],"q":"The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)(g) when its concentration exceeds: ,  0,001 % in leave-on products ,  0,01 % in rinse-off products","c":"A"}},"eu-2023-1545":{"name":"Regulation (EU) 2023/1545 (labelling of fragrance allergens)","body":"EU","kind":"a labelling condition, extended to more fragrance allergens","href":"/perfumery/regulation/eu-2023-1545.html","ev":{"e":"documented","s":[{"t":"Commission Regulation (EU) 2023/1545 of 26 July 2023 (labelling of fragrance allergens)","h":"https://eur-lex.europa.eu/eli/reg/2023/1545/oj"}],"q":"Therefore, an obligation to individually label those fragrance allergens should be introduced in Annex III to Regulation (EC) No 1223/2009 when their concentration exceeds 0,001 % in leave-on products and 0,01 % in rinse-off products.","c":"A"}},"ifra-rose-ketones":{"name":"IFRA Standard: Rose ketones","body":"IFRA","kind":"RESTRICTION","href":"/perfumery/regulation/ifra-rose-ketones.html","ev":{"e":"documented","s":[{"t":"International Fragrance Association (IFRA)","h":"https://d3t14p1xronwr0.cloudfront.net/docs/standards/IFRA_STD_077.pdf"}],"q":"RECOMMENDATION: RESTRICTION MAXIMUM ACCEPTABLE CONCENTRATIONS IN THE FINISHED PRODUCT (%)","c":"A"}}},"variants":[{"id":"v1","label":"The rose as written","kind":"teaching variant, modeled","basis":"the record as written","why":{"e":"house interpretation","c":"B","n":"the accord record’s structure field: the choice of the four molecules is the house’s; each one’s place in rose oil is documented on its component","v":"The rose as the record writes it: phenylethyl alcohol, citronellol and geraniol for the body, and a trace of β-damascenone."},"links":[],"parts":{"phenylethyl-alcohol":45,"citronellol":30,"geraniol":24.9,"beta-damascenone":0.1},"grades":{},"partsEv":{"e":"modeled","c":"C","n":"teaching proportions, a house interpretation for learning: modeled, not measured, not a formula, not for making"}},{"id":"v2","label":"Citronellol-forward","kind":"teaching variant, modeled","basis":"house teaching example","why":{"e":"house interpretation","c":"C","n":"a house teaching example: no filed source documents this version, and it is not a reconstruction of any perfume","v":"A house teaching example: more citronellol and less of the others, the β-damascenone trace halved, to show how the balance of the body moves the words on record."},"links":[],"parts":{"phenylethyl-alcohol":35,"citronellol":45,"geraniol":19.95,"beta-damascenone":0.05},"grades":{},"partsEv":{"e":"modeled","c":"C","n":"teaching proportions of a teaching variant, a house interpretation for learning: modeled, not measured, not a formula, not for making"}},{"id":"v3","label":"Damascenone-forward","kind":"teaching variant, modeled","basis":"house teaching example","why":{"e":"house interpretation","s":[{"t":"International Fragrance Association (IFRA)","h":"https://d3t14p1xronwr0.cloudfront.net/docs/standards/IFRA_STD_077.pdf"}],"q":"INTRINSIC PROPERTY DRIVING RISK MANAGEMENT: DERMAL SENSITIZATION","c":"C","n":"the standard is documented (its Regulation record); the version is the house’s teaching choice. US law: not on record","v":"A house teaching example: five times the β-damascenone, to show how far a trace with a low measured odour threshold reaches. β-Damascenone is one of the rose ketones an IFRA Standard (the industry’s own standard, not law) restricts by concentration in finished products; this teaching accord is not a finished product and is not assessed."},"links":[{"href":"/perfumery/regulation/ifra-rose-ketones.html","label":"IFRA Standard: Rose ketones","kind":"regulation","words":"IFRA"}],"parts":{"phenylethyl-alcohol":45,"citronellol":27,"geraniol":27.5,"beta-damascenone":0.5},"grades":{},"partsEv":{"e":"modeled","c":"C","n":"teaching proportions of a teaching variant, a house interpretation for learning: modeled, not measured, not a formula, not for making"}}]}